What were the three most important factors in the Confederacy's defeat in the Civil War?

There were
many factors which played a role in
shaping the Confederacy's defeat in the Civil War, and I'd
hesitate to winnow
things down to just three. However, for the purposes of this answer, I'd

focus upon the Union's clear advantages in production and population (advantages which
proved
overwhelming in the long run), the impact of long-term military
strategy, and the South's
continued reliance on slavery, which would serve to
isolate it from potential allies such as
Great Britain and (after the passage
of the Emancipation Proclamation) would serve as a rallying
cry among those
opposed to slavery.

Of these three, I believe the most

important was the sheer quantitative advantages the Union possessed. The Union had a
much larger
population (giving it a far greater ability to replenish losses,
an advantage Grant would use
to...