What are the sources of evil and human misfortune in Voltaire's Candide?

The main
causes of human suffering and dissatisfaction in s come from a few select
sources. The top five are the following: religion, war/violence, nature, sex, and lack of
reason/intelligence. These ideas make up the majority of Voltaire's plot, as he uses them to
show a pessimistic world.

From the very first chapter, sex is used to create
a negative experience for two main characters. Candide is arrested for attempting to kiss
Cunegonde when she shows interest in him after hearing Pangloss having sex with a servant.
Pangloss is also punished, as he eventually contracts syphilis.

Violence and
war are prevalent throughout...